A novel radial water tread maze tracks age-related cognitive decline in mice

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A novel radial water tread maze tracks age-related cognitive decline in mice

There is currently no treatment and cure for age-related dementia and cognitive impairment in humans. Mice suffer from age-related cognitive decline just as people do, but assessment is challenging because of cumbersome and at times stressful performance tasks. We developed a novel radial water tread (RWT) maze and tested male C57BL/6 (B6) and C57BL/6 x Balb/c F1 (CB6F1) mice at ages 4, 12, 20,...

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ژورنال

عنوان ژورنال: Pathobiology of Aging & Age-related Diseases

سال: 2013

ISSN: 2001-0001

DOI: 10.3402/pba.v3i0.20679